2-Panel Drug Test (Strip) (BAR,BZD) description:

Los Angeles based Diagnostic Automation/Cortez Diagnostics, Inc. maker of many drug testing kits, offers a 2-panel Drug Test for Barbiturate (BAR) and Benzodiazepine (BZD) drugs. This multi drug test kit is designed for qualitative determination of drug substances in human urine specimen. Count on us for dependable rapid diagnostic kits.

The two panel drug test- Barbiturate and Benzodiazepine Drug Testing device is based on the principle of specific immunochemical reaction between antibodies and antigens to analyze particular compounds in human urine specimen. The assay relies on the competition for binding antibody between drug conjugate and free drug which may be present in the urine specimen being tested. When the Barbiturate or Benzodiazepine drug is present in the urine specimen, it competes with drug conjugate for the limited amount of antibody-dye conjugate. When the amount of the barbiturate or benzodiazepine drug is equal or more than the cut-off, it will prevent the binding of drug conjugate to the antibody. Therefore, a positive urine specimen on the 2-panel drug test - Barbiturate and Benzodiazepine Drug Test will not show a colored band on the test line zone, indicating a positive result, while the presence of a colored band indicates a negative result. A control line is present in the test window to work as procedural control. This colored band should always appear on the control line zone if the 2-panel drug test - barbiturate and benzodiazepine drug testing device is stored in good condition and the 2 panel drug test - barbiturate and benzodiazepine drug test is performed appropriately.

Barbiturates (BAR) are a group of prescription drugs that are frequently abused. Barbiturate drugs can depress the central nervous system. Acute higher doses of barbiturate drugs induce exhilaration, sedation and respiratory depression. More acute responses to barbiturate drugs produce respiratory collapse and coma. The effects of short-acting barbiturate drugs, such as secobarbital last 3 to 6 hours. The effects of long-acting barbiturate drugs such as phenobarbital last 10 to 20 hours. Short-acting barbiturate drugs normally remain detectable in urine for 4 to 6 days, while long-acting barbiturate drugs can be detected for up to 30 days. Barbiturate drugs are excreted in the urine in unchanged forms, hydroxylated derivatives, carboxylated derivatives and glucuronide conjugates.

Benzodiazepines (BZD) are a class of widely prescribed central nervous system depressants which have anxiolytic, hypnotic, anti-convulsant and muscle relaxant effects. Chronic abuse of benzodiazepine drugs can result in addiction and tardive dyskinnesia. Acute higher doses of benzodiazepine drugs lead to drowsiness, dizziness, muscle relaxation, lethargy, coma and possible death. The effects of benzodiazepine drug use last 4 – 8 hours. Many of the benzodiazepine drugs share a common metabolic route, and are excreted as oxazepam and its glucuronide in urine. Oxazepam is detectable in the urine for up to 7 days after drug use.

The multi drug test kit Barbiturate (BAR) and Benzodiazepine (BZD) Drug Test provides only a preliminary analytical test result. A more specific alternative chemical method must be used in order to obtain a confirmed analytical result. Gas chromatography/ mass spectrometry (GC/MS) has been established as the preferred confirmatory method by the Substance Abuse Mental Health Services Administration (SAMHSA). Clinical consideration and professional judgment should be applied to any drug of abuse test result, particularly when preliminary positive results are indicated.

The optional built-in Adulteration Test is for validation of urine specimen’s integrity and must not be used for In Vitro diagnostic use. The cutoff level for this 2-panel drug test - Barbiturate (BAR) and Benzodiazepine (BZD) Drug Test is 300 ng/ml secobarbitol and 300 ng/ml of oxazepam. For customized cutoff level barbiturate and benzodiazepine drug tests, please contact Customer Service. This multi panel drug test - Barbiturate (BAR) and Benzodiazepine (BZD) Drug Test is also available in cassette or strip format.