4-Panel Drug Test (Strip) (BZD,COC,MOR,THC) description:

Los Angeles based provider of rapid diagnostic tests, Diagnostics Automation/Cortez Diagnostics, Inc. offers a Multi Panel Drug Test for any combination drugs: Benzodiazepine (BZD), Cocaine (COC), Morphine, (MOR), and Marijuana (THC). Our drug testing kits, including this 4 panel drug test, are designed for qualitative determination of drug substances in human urine specimen.

The multi panel drug test device is based on the principle of specific immunochemical reaction between antibodies and antigens to analyze particular compounds in human urine specimen. The assay relies on the competition for binding antibody between drug conjugate and free drug which may be present in the urine specimen being tested. When the Benzodiazepine (BZD), Cocaine (COC), Morphine, (MOR), or Marijuana (THC) drug is present in the urine specimen, it competes with drug conjugate for the limited amount of antibody-dye conjugate. When the amount of the Benzodiazepine (BZD), Cocaine (COC), Morphine, (MOR), or Marijuana (THC) drug is equal or more than the cut-off, it will prevent the binding of drug conjugate to the antibody. Therefore, a positive urine specimen on the multi panel drug test - Benzodiazepine (BZD), Cocaine (COC), Morphine, (MOR), and Marijuana (THC) Drug Test will not show a colored band on the test line zone, indicating a positive result, while the presence of a colored band indicates a negative result. A control line is present in the test window to work as procedural control. This colored band should always appear on the control line zone if the multi panel drug test - Benzodiazepine (BZD), Cocaine (COC), Morphine, (MOR), and Marijuana (THC) drug testing device is stored in good condition and the multi panel drug test - Benzodiazepine (BZD), Cocaine (COC), Morphine, (MOR), and Marijuana (THC) Drug Test is performed appropriately.

Benzodiazepines are a class of widely prescribed central nervous system depressants which have anxiolytic, hypnotic, anti-convulsant and muscle relaxant effects. Chronic abuse of benzodiazepine drugs can result in addiction and tardive dyskinnesia. Acute higher doses of benzodiazepine drugs lead to drowsiness, dizziness, muscle relaxation, lethargy, coma and possible death. The effects of benzodiazepines drug use last 4 to 8 hours. Many of the benzodiazepine drugs share a common metabolic route, and are excreted as oxazepam and its glucuronide in urine. Oxazepam is detectable in the urine for up to 7 days after drug use. The cutoff level for this multi panel drug test for the benzodiazepine drug is 300 ng/ml of oxazepam. Cocaine (COC) is derived from the leaves of the cocoa plant.

The cocaine drug is a potent central nervous system stimulant as well as a local anesthetic. Some of the psychological effects induced by the cocaine drug are: euphoria, confidence and a sense of increased energy, accompanied by increased heart rate, dilation of the pupils, fever, tremors and sweating. Continued ingestion of the cocaine drug could induce tolerances and physiological dependency which leads to its abuse. The cocaine drug is used by smoking, intravenous, intransal or oral administration and excreted in the urine primarily as benzoylecgonine in a short period.

Benzoylecgonine has a biological half-life of 5 to 8 hours, which is much longer than that of the cocaine drug ( 0.5 to 1.5 hours), and can be generally detected for 12 to 72 hours after cocaine drug use or exposure. The cutoff level for this multi panel drug test for the cocaine drug is 300 ng/ml of benzoylecgonine.

The Morphine drug (MOR) is an opioid analgesic, the principal and most active alkaloid of opium. Opiate Opioid analgesics are comprised of a large group of substances that control pain by depressing the central nervous system.

The morphine drug is a powerful narcotic analgesic, and its primary clinical use is in the management of moderately severe to severe pain. After heroin, morphine has the greatest potential for addiction of all narcotic analgesics. Acute high doses of opiates-heroin-morphine drugs used by abusers or addicts can cause depressed coordination, disrupted decision, decreased respiration, hypothermia and coma. The morphine drug is excreted unmetabolized and is the marker metabolic product of opiate drugs. The morphine drug and the drug morphine glucuronide are detectable in urine for several days after opiate drug dose. The cutoff level for this multi panel drug test for the morphine drug is 300 ng/ml of morphine.

The agents of the Marijuana Drug (THC) that cause various biological effects in humans are called cannabinoid. Cannabinoid is a central nervous stimulant that alters mood and sensory perceptions, produces loss of coordination, impairs short term memory, and produces symptoms of anxiety, paranoia, depression, confusion, hallucination, and increased heart rate. Large doses of cannabinoid could cause the development of tolerances and physiological dependency and lead to abuse. A tolerance to the cardiac and psychotropic effects of the marijuana drug can occur and withdrawal syndrome produces restlessness, insomnia, anorexia and nausea. ␣9-THC is the primary active ingredient in cannabinoids. The main metabolite excreted in the urine is 11-nor-␣9-THC-9-COOH, which are found within hours of exposure and remain detectable in the urine for 3-10 days after smoking. The cutoff level for this multi panel drug test for the marijuana drug is 50 ng/ml of 11-nor-D9-THC-9-COOH.

The multi panel drug test kit-provides only a preliminary analytical test result. A more specific alternative chemical method must be used in order to obtain a confirmed analytical result. Gas chromatography/ mass spectrometry (GC/MS) has been established as the preferred confirmatory method by the Substance Abuse Mental Health Services Administration (SAMHSA). Clinical consideration and professional judgment should be applied to any drug of abuse test result, particularly when preliminary positive results are indicated.

The optional built-in Adulteration Test is for validation of urine specimen’s integrity and must not be used for In Vitro diagnostic use. For customized cutoff levels for any multi panel drug tests, please contact Customer Service. This multi panel drug test - Benzodiazepine (BZD), Cocaine (COC), Morphine, (MOR), and Marijuana (THC) Drug Test, is available in cassette, strip, or cup format.