3-Panel Drug Test (Strip) (BZD,MAD,MOR) description:

Los Angeles based Diagnostic Automation/Cortez Diagnostics, Inc., maker of a variety of rapid diagnostic tests, offers a 3-panel Drug Test - (BZD) Benzodiazepine drug test, MTD drug test, and (MOR) Morphine drug test.  Our drug testing kits are designed for qualitative determination of drug substances in human urine specimen.

The three panel drug test - (BZD) Benzodiazepine drug test, (MTD) Methadone drug test, and (MOR) Morphine Drug Testing device is based on the principle of specific immunochemical reaction between antibodies and antigens to analyze particular compounds in human urine specimen. The assay relies on the competition for binding antibody between drug conjugate and free drug which may be present in the urine specimen being tested.  When the Benzodiazepine, Methadone, or Morphine drug is present in the urine specimen, it competes with drug conjugate for the limited amount of antibody-dye conjugate. When the amount of the benzodiazepine, methadone, or morphine drug is equal or more than the cut-off, it will prevent the binding of drug conjugate to the antibody. Therefore, a positive urine specimen on the 3-panel drug test - (BZD) Benzodiazepine drug test, (MTD) Methadone drug test, and (MOR) Morphine Drug Test will not show a colored band on the test line zone, indicating a positive result, while the presence of a colored band indicates a negative result.  A control line is present in the test window to work as procedural control. This colored band should always appear on the control line zone if the 3-panel drug test - (BZD) Benzodiazepine drug test, (MTD) Methadone drug test, and (MOR) Morphine drug testing device is stored in good condition and the 3 panel drug test - (BZD) Benzodiazepine drug test, (MTD) Methadone drug test, and (MOR) Morphine drug test is performed appropriately.

Benzodiazepines (BZD) are a class of widely prescribed central nervous system depressants which have anxiolytic, hypnotic, anti-convulsant and muscle relaxant effects. Chronic abuse of benzodiazepine drugs can result in addiction and tardive dyskinnesia. Acute higher doses of benzodiazepine drugs lead to drowsiness, dizziness, muscle relaxation, lethargy, coma and possible death. The effects of benzodiazepine drug use last 4 to 8 hours. Many of the benzodiazepine drugs share a common metabolic route, and are excreted as oxazepam and its glucuronide in urine.  Oxazepam is detectable in the urine for up to 7 days after drug use.

Methadone (MTD) is a synthetic opioid, clinically available. The methadone drug is used clinically for the treatment of severe pain and in maintenance programs for morphine and heroin addicts.  The Methadone drug acts on the central nervous and cardiovascular systems to produce respiratory and circulatory depression. The Methadone drug also produces miosis and increases the tone of smooth muscle in the lower gastrointestinal tract while decreasing the amplitude of contractions.  Acute higher doses of the methadone drug induce analgesia, sedation, respiratory depression and coma.  After methadone administration, the major urinary excretion products are methadone and its metabolites, EDDP and EMDP.  Large individual variations in the urine excretion of the methadone drug are output of methadone from 5-22%. Typically, following a 5 mg oral dose, the methadone drug and EDDP account for 5% of the dose in the 24-hour urine.  In those individuals on maintenance therapy, the methadone drug may account for 5 to 50% of the dose in the 24-hour urine and EDDP may account for 3 to 25% of the dose.

The Morphine drug (MOR) is an opioid analgesic, the principal and most active alkaloid of opium.  Opiate Opioid analgesics are comprised of a large group of substances that control pain by depressing the central nervous system. The morphine drug is a powerful narcotic analgesic, and its primary clinical use is in the management of moderately severe to severe pain. After heroin, morphine has the greatest potential for addiction of all narcotic analgesics.  Acute high doses of opiates-heroin-morphine drugs used by abusers or addicts can cause depressed coordination, disrupted decision, decreased respiration, hypothermia and coma. The morphine drug is excreted unmetabolized and is the marker metabolic product of opiate drugs.  The morphine drug and the drug morphine glucuronide are detectable in urine for several days after opiate drug dose.

The three panel test kit - (BZD) Benzodiazepine drug test, (MTD) Methadone drug test, and (MOR) Morphine Drug Test provides only a preliminary analytical test result. A more specific alternative chemical method must be used in order to obtain a confirmed analytical result.  Gas chromatography/ mass spectrometry (GC/MS) has been established as the preferred confirmatory method by the Substance Abuse Mental Health Services Administration (SAMHSA). Clinical consideration and professional judgment should be applied to any drug of abuse test result, particularly when preliminary positive results are indicated.

The optional built-in Adulteration Test is for validation of urine specimen's integrity and must not be used for In Vitro diagnostic use.  The cutoff level for this 3-panel drug test - (BZD) Benzodiazepine drug test, (MTD) Methadone drug test, and (MOR) Morphine Drug Test is 300 ng/ml of oxazepam, 300 ng/ml of methadone, and 300 ng/ml of morphine.  For customized cutoff level benzodiazepine, methadone, and morphine drug tests, please contact Customer Service.  This 3 panel drug test - (BZD) Benzodiazepine drug test, (MTD) Methadone drug test, and (MOR) Morphine Drug Test is also available in cassette or strip format.