Methylphenidate drug test (MPD) (strip) description:

The Cortez Diagnostics, Inc. DOA (Drug of Abuse), Methylphenidate Drug Test (MPD Drug Test), is an immunochromatography based one step in vitro test. Our Methylphenidate drug test kits are designed for qualitative determination of methylphenidate drug substances in human urine specimen. This assay has not been evaluated in the point of care location and is for use by Healthcare Professionals only.

Methylphenidate is most commonly known by the Novartis trademark name Ritalin, which is an instant-release racemic mixture.  There also exists a variety of formulations and generic brand names.  The Methylphenidate drug  is a psychostimulant drug for the treatment of attention-deficit hyperactivity disorder, Postural Orthostatic Tachycardia Syndrome, and narcolepsy.  The methylphenidate drug may also be prescribed for off-label use in treatment-resistant cases of lethargy, depression, neutral insult, obesity, and rarely for other psychiatric disorders such as Obsessive-Compulsive Disorder.  The methylphenidate drug, like other stimulants, increases dopamine levels.  The abuse potential of the methylphenidate drug is increased when the methylphenidate drug is crushed and snorted or when it is injected producing effects almost identical to the cocaine drug.  Cocaine-like effects can also occur with very large doses of the methylphenidate drug taken orally.  The methylphenidate drug has a high potential for drug dependence and addictive abuse due to its similar pharmacological connection to cocaine and amphetamines.  Internationally, the methylphenidate drug is a Schedule II drug under the Convention on Psychotropic Substances.  In the United States, the methylphenidate drug is classified as a Schedule II controlled substance, the designation used for substances that have a recognized medical value but present a high likelihood for abuse because of their addictive potential.

The Methylphenidate Drug Testing device is based on the principle of specific immunochemical reaction between antibodies and antigens to analyze particular compounds in human urine specimen. The assay relies on the competition for binding antibody between drug conjugate and free drug which may be present in the urine specimen being tested.  When the methylphenidate drug is present in the urine specimen, it competes with drug conjugate for the limited amount of antibody-dye conjugate. When the amount of the methylphenidate drug is equal or more than the cut-off, it will prevent the binding of drug conjugate to the antibody. Therefore, a positive urine specimen on the Methylphenidate Drug Test will not show a colored band on the test line zone, indicating a positive result, while the presence of a colored band indicates a negative result.  A control line is present in the test window to work as procedural control. This colored band should always appear on the control line zone if the Methylphenidate drug testing device is stored in good condition and the Methylphenidate drug test is performed appropriately.

This Methylphenidate Drug Test (MPD Drug Test) provides only a preliminary analytical test result. A more specific alternative chemical method must be used in order to obtain a confirmed analytical result. Gas chromatography/ mass spectrometry (GC/MS) has been established as the preferred confirmatory method by the Substance Abuse Mental Health Services Administration (SAMHSA). Clinical consideration and professional judgment should be applied to any drug of abuse test result, particularly when preliminary positive results are indicated.

The optional built-in Adulteration Test is for validation of urine specimen integrity and must not be used for In Vitro diagnostic use. The cutoff level for this Methylphenidate Drug Test (MPD Drug Test) is 300 ng/ml of methylphenidate.  For customized cutoff level methylphenidate drug tests, please contact Customer Service.  This Methylphenidate Drug Test (MPD Drug Test) is available in multi-panel, cassette, strip, or cup format.

The optional built-in Adulteration Test is for validation of urine specimen integrity and must not be used for In Vitro diagnostic use. The cutoff level for this Methylphenidate Drug Test (MPD Drug Test) is 300 ng/ml of methylphenidate.  For customized cutoff level methylphenidate drug tests, please contact Customer Service.  This Methylphenidate Drug Test (MPD Drug Test) is available in multi-panel, cassette, strip, or cup format. Our company is your source for drug tests and other rapid diagnostic tests.