Malaria Rapid test
Malaria is a serious parasitic disease characterized by fever, chills,
and anemia and is caused by a parasite that is transmitted from one human to
another through the bite of infected Anopheles mosquitoes. There are four kinds
of malaria that can infect humans: Plasmodium falciparum, P. vivax, P. ovale, and
P. malariae. In humans, the parasites (called sporozoites) migrate to the liver
where they mature and release another form, the merozoites. The disease now
occurs in more than 90 countries worldwide, and it is estimated that there are
over 500 million clinical cases and 2.7 million malaria-caused deaths per year.
At present, malaria is diagnosed by looking for the parasites in a drop
of blood. Blood will be put onto a microscope slide and stained so that the
parasites will be visible under a microscope.
We offer two formats of the test. One test, the Malaria (Pan-LDH) W/B RapiCard™
InstaTest Cat# 172120-25, can detect all four species of malaria Plasmodium
falciparum, Plasmodium vivax, Plasmodium ovale, and Plasmodium malariae. This pan-LDH
Antigen Test contains a membrane strip, which is pre-coated with anti-pan LDH
monoclonal antibodies on the test line region of the strip. When a Whole Blood specimen is applied at one
end of the membrane and following the application of the assay buffer, it
reacts with the colloidal gold-anti-pan LDH antibody that has already been
applied to the specimen pad. The mixture then migrates chromate-graphically
towards the other end of the membrane and reacts with the monoclonal antibodies
previously placed on the test line region. If the blood contains one or more of
the four Malaria species, a colored line will appear in the test line region,
showing a positive result. The absence
of the colored line in the test region indicates a negative result; therefore
the whole blood does not contain detectable levels of any of the Malaria
species.
The other format, Malaria (Pf/Vivax) W/B RapiCard™
InstaTest Cat# 172110-25, will differentiate between the two species: Plasmodium falciparum anf Plasmodium Viavax. This Malaria pf (HRP II) / pv (LDH) Antigen 172110-25
Test contains a membrane strip, which is pre-coated with two monoclonal
antibodies as two separate lines across a test strip. One monoclonal antibody (test line 1) is
specific to the P. falciparum histidine rich protein-2 (Pf HRP-2) and another
monoclonal antibody (test line 2) is specific to the lactate dehydrogenase of
the P. vivax species (pvLDH). A Conjugate pad is dispensed with monoclonal
antibodies conjugated to colloidal gold, which are specific to P. falciparum
histidine rich protein-2 (Pf HRP-2) and specific to the lactate dehydrogenase
of P. vivax. Therefore, the antigen of Plasmodium falciparum and Plasmodium
vivax can be differentially detected.
Malaria (P.f./Vivax) WB Rapid Test (Cassette) RapiCard™ InstaTest
Malaria (Pan-LDH) WB Rapid Test (Cassette) RapidCard™ Insta Test
